What key difference in our bodys immune response would be elicited by a vaccine administered orally rather than intravenously?

There are many autoimmune diseases wherein the immune system attacks the bodys own cells. These Show more A. There are many autoimmune diseases wherein the immune system attacks the bodys own cells. These diseases seem to indicate a flaw in the immune system and it seems odd that natural selection has not led to an immune system with a better concept of self. Why have these autoimmune responses remained a part of the immune system? What are some situations where it would be advantageous for the immune system to target the bodys cells? B. Vibrio cholerae is a bacterium that enters the body through the fecal-oral route and can lead to severe diarrhea and in some cases death. There are an estimated 3-5 million cases per year with 100000 deaths resulting from infection. i. What is the main reason that our body may not want to induce a potent immune attack of this type of pathogen? ii. Although vaccines to cholera do exist they are only about 50% effective. Since the bacteria infect the gut oral vaccines routes have been more effective than injected vaccines. What key difference in our bodys immune response would be elicited by a vaccine administered orally rather than intravenously?