Explain briefly why a defect in clearance or engulfment of apoptotic bodies might lead to autoimmune disease.

Explain briefly why a defect in clearance or engulfment of apoptotic bodies might lead to autoimmune disease.

In patients with autoimmune diseases the adaptive immune system recognizes some normal cells or pro Show more In patients with autoimmune diseases the adaptive immune system recognizes some normal cells or proteins as though they were foreign. Defects in the regulated apoptosis and clearance of cells are thought to cause or exacerbate some autoimmune diseases. A. Explain briefly which cells normally undergo apoptosis and can cause autoimmune disease if they survive inappropriately. B. Explain briefly why a defect in clearance or engulfment of apoptotic bodies might lead to autoimmune disease.