Single Strand Binding Protein Essay

Single strand binding protein refers to a means by which the cells prevent opened DNA from re-establishing pre-opening of the double helix conformation at replication fork during the process of DNA replication. In simple terms, single strand binding protein binds to the single-stranded regions of the DNA preventing them from annealing prematurely in order to protect single-stranded DNA from nucleases digestion while removing the secondary structure from DNA allowing for effective functioning of the other enzymes on it.Single Strand Binding Protein Essay

Production of single stranded DNA occurs during every aspect of metabolism of DNA. This refers to recombination, replication and repair. It also helps in stabilizing the single-stranded DNA. This is because this protein binds to different proteins while modulating function of the involved proteins in different process.

Single strand binding protein has been seen in both organisms and viruses from the bacteria to the humans. The
only living organisms that do not have the single strand binding protein are the Thermoproteales. This is a group of the extremophile archaea. In these organisms, single strand binding protein is replaced by ThermoDBP which is also a protein.