A dose-limiting toxicity or side effect is one that results in dose delay, dose reduction, or dose/drug discontinuation. A dose-limiting toxicity is not one where only the infusion rate is changed (ex. infusion reaction with rituximab) but where a true modification to the dose occurs. To answer this discussion question, reflect on some of the more challenging dose-limiting toxicities you assess and manage in your practice. If you need help deciding on a dose-limiting toxicity to discuss, refer to Table 7 in the course eBook (Characteristics of Chemotherapeutic Agents). In addition the course eBook is a great reference for assessment and evidence-based strategies.

Answer the following questions completely with details to earn credit for post:

1. Pick ONE dose-limiting toxicity related to a particular chemotherapy agent (actually state the agent in your post).
2. Provide two (2) key components of your nursing assessment that should be routinely performed to identify or monitor the one toxicity you chose.
3. Discuss two (2) evidence-based pharmacologic and/or non-pharmacologic management strategies for toxicity you chose.