The advancement in developmental neurobiology allowed scientists to establish the influence of early childhood experiences on violent behavior in adulthood. Brain imaging demonstrated that diminished fear response was present in those children who had an increased tendency for criminal behavior (Sterzer, 2010). The experimental studies demonstrated that exposure to chronic stress early in life results in abnormal changes in the amygdala, hippocampus, and prefrontal cortex responsible for fear response, memory, and decision making, respectively (Shonkoff et al., 2012). Prolonged exposure to child abuse or parental substance use led to chronically elevated cortisol levels in children and impaired brain functions (Shonkoff et al., 2012). Mild stress with appropriate parental support enables children’s development and growth. The stress of a greater magnitude may have negative consequences on cognitive and behavioral functions, causing anti-social behavior in adulthood (Shonkoff et al., 2012). The supportive environment reduces the negative effect of stress on the brain. It also reduces future morbidities, indicating the importance of protective factors to mitigate the risk factors’ proximal and distant effects (Shonkoff et al., 2012). These risk and supportive factors should be used for timely intervention to prevent adverse outcomes.