When inappropriately and increase of respiratory rate from the initial assessment. Q4. Detail the pharmacological intervention you are able to perform as a paramedic and using pharmacological principles justify the dose rate and route of administration you would use. If your first attempt at reversal is unsuccessful, what would be your strategy and why? (10 marks). In this case, the patient should be given a trial dose of 0.1 mg to 0.2 mg of Naloxone via the intravenous line to counter the effects of heroin on the central nervous system (Mitchell & Medzon, 2005). Following administration, the patient is expected to have an increase heart rate, pupillary dilation, and rousing from a state of somnolence case reports’, Journal of Medical Case Reports, vol. 2, pp.16 Thomson, D, Melmon, L, Richardson, A, Cohn, K & Steinbrunn, W 2003, ‘Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans’. Ann Intern Med, vol. 78, no. 4, pp. 499–508. Toutan, P 2004, ‘Volume of Distribution’, Journal of Applied Pharmacology and Therapeutics, vol. 27, pp. 441-453. , ‘Clinical pharmacokinetics of local anaesthetics’, Clinical Pharmacokinetics, vol. 4, no. 4, pp.241–278. Verbeeck, R 2008, ‘Pharmacokinetics and dosage adjustments in patients with hepatic dysfunction’, European Journal of Clinical Pharmacology, vol. 64, pp. 1147-1161…. increase more than three times the normal value. Steady state concentrations in such? Pharmacology Administration of medication in hospitals requires a lot more than giving patients their medication. According to the AFH rules, caregivers must always be aware of every patient’s medication administration schedule, why the patient is being given the medication, its effects and any side effects that could arise. Medication administration process includes getting medical orders, writing medical orders on the (MAR) medical administration record, comparing the medical orders with the ones on the MAR to ensure they are correct, delivering and administering the medication to the patients, monitoring the patient’s progress and recording, storing and getting rid of expired, unused and contaminated medication into the small intestines after oral administration rapidly and reliably. Both agents have dose-limited absorption. Referring to the pharmacodynamics, Gabapentin has analgesic properties that are considered therapeutic. Carbamazepine decreases the conductivity of Na+ also inhibits the ectopic discharges and thus alleviates pain. In terms of metabolism, in humans the two drugs undergo metabolism corresponding to N-Methyl metabol though minimally. The drugs do not have interactions with other drugs as they undergo minimal metabolism (Bennet & Simpsons, 2004). Comparison studies for efficacy have been carried out and research conducted shows that Gabapentin is more suited for use as it has clearly shown analgesic effects and the dementia worsens, doctors begin prescription with Namenda which has been approved for the treatment of advanced forms of the disease. In some cases both the drugs are also given in combination. Screening of dementia in a primary care setting initially utilizes a rapid screening tool for memory loss such as the Mini-Cog or Family Questionnaire which are easy and can be administered by nurses or a medical assistant. If these initial tools are indicative of memory loss the patient is then subjected to a second cognitive assessment using tools such as Mini Mental State Examination which also take about 10-15 minutes to administer. Based on the scores the person is referred to a dementia specialist Retin A/ Accutane (Advanced pharmacology) Retin A/ Accutane (Advanced pharmacology) Retin A is a Tretinoin composed of Retinoic acid or Vitamin A acid and is available in the forms of creams, gels and liquids for topical administration. The main use of the topical formulations is for the treatment of acne vulgaris (Spratto & Woods, 2009). Retin A has also shown to fade dark spots, improve skin texture and smoothen the skin texture because it works at a cellular level (Wadyka, 2006). Retin A is used commonly for treatment or reduction of blackheads and whiteheads. Topical tretinoin works by decreasing micro comedone formation and reduces the cohesiveness of the follicular epithelial cells. It also reduces the mitotic activity… A/ Accutane Nursing The impact of proper medical observation when dealing with chronic disease Introduction Hypertension, coronary artery disease, Type 2 diabetes mellitus, and paroxysmal atrial fibrillation are very dangerous diseases most of them are caused by the type of food that people take. The aged people they get this type of diseases because there is too much accumulation of fats in the blood stream that causes the blood plumbing to experience hardship in pushing the blood within the blood stream thus causing (George kruscik, 2013). In some other serious cases like diabetes 2 due to poor diet as someone is coming to a aging point the body system becomes unable to control the body sugar due to failure of insulin thus. which blocks the movement of the sperm beyond the cervix. There are many different types of progesterones like synthetic or oral progesterone, crinone, injectible progesterone and progesterone suppositories. Before recommending an oral contraceptive pill which is usually a combined oral contraceptive pill (COCP) to the client, a detailed clinical history must be taken. The history should cover information like the previous and current medications taken by the client, herbal and over the counter remedies and drug usage. In case of women above 35 years and women with a history of cardiovascular disease, diabetes, migraines, gall bladder disease and pulmonary hypertension, COCP recommendation should be avoided (Petitti,……Busulfan Case Study.NUR 635: Advanced Pharmacology Essay 

Busulfan is a chemotherapeutic agent used mostly in the long term management of Chronic Myeloid Leukaemia. It is sometimes also given in high doses before bone marrow or stem cell transplantations for leukaemia and other cancer types. The tablet form of the drug is referred to us Myleran while the injection form is known us Busilvex. The brand name is therefore Myleran while the generic name is Busulfan. I will be looking at the drug’s pharmacology and therapeutic importance. Structure of Busulfan (Source, drug bank). Classification. In terms of classification Busulfan is an organic sulphite i.e. contains [SO3]2-NUR 635: Advanced Pharmacology Essay Paper