Sickle Cell Anemia: Detection, Complications, and Transplantation of Liver

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Sickle Cell Anemia: Detection, Complications, and Transplantation of Liver

“The Manual Process of Detection of Sickle Cell Anemia”

Lack of enough healthy blood cells causes anemia since the red blood cells are responsible in transporting the oxygen to all parts of the body. The inheritable disease is caused when a person gets two abnormal genes from each of the parents. Red blood cells are elastic and move easily through the blood vessels, but in sickle cell anemia, the red blood cells are crescent-shaped (Vasundhara & Krishna, 2018). The sticky cells can be stuck to form small blood vessels that block or slow the blood and oxygen flow to the body’s parts. There is no cure, but treatment that can only prevent complications and relieve pain for the people living with sickle cell anemia.

The granulometric analysis is implemented to separate the red blood cells from the other components of the blood. Then, an improved watershed transform algorithm is used to separate the cluster cells (Vasundhara & Krishna, 2018). Even though red blood cells are considered cells, they lack a nuclear of the Deoxyribonucleic acid and the components to express and synthesize proteins. It then shows the exact separation of the red blood cells into getting the blood cell count splitting the groups. It improves the accuracy making the results to 98.5% in identifying sickle cell anemia and 97.6% in the separation of the red blood cells (Nacif et al., 2018). The techniques and physical processes to detect anemia needs proper pipetting, hence, are unspecific.

“Liver Transplantation from a Deceased with Sickle Cell Anemia”

Liver transplantation has been successful due to advances in technology and has increased the value of immunosuppressive drugs and improved the quality of life of the patients. The article supports the importance of using safe donors and uses an example of a deceased liver donor involved in liver transplantation (Nacif et al., 2018). The liver donor was a young male twenty-two years old who had complications with his brain that later stopped functioning completely. The donor surgery was successful and was not associated with any difficulties, and both of the deceased patient’s kidneys were donated to different recipients and centers. Liver transportation was done, and the recipient was a thirty-seven-year-old woman who had the same blood group as the donor and was diagnosed with hepatitis B virus. She received four units of red blood cells, three units of platelets, and eight plasma units during the surgery (Nacif et al., 2018). She received proper postoperative care, but still developed an acute kidney failure. After successful liver transplantation between the woman and the deceased, doctors reported that sickle cell anemic patients could help in liver replacement, however, it is advised to use safe donors.

“Understanding the Complications of Sickle Cell Anemia”

To improve the quality of life and health results, correct educational information should be given by the nurses who look after anemic patients. Many people worldwide have sickle cell disease, most commonly from Saudi Arabian dessert, India, Caribbean, United States of America, and Central America. Patients mainly experience acute severe difficulties, such as chest syndromes and kidney failures, throughout their life (Tanabe et al., 2019). People who have sickle cell anemia are commonly to have priapism, and the healthcare providers should remind the patients to pay attention to the causing factors and let them know it is a complication for anemic patients. For effective management of anemia is usually aimed at avoiding pain and relieving symptoms hence regular check-up by the healthcare team is necessary. Patients are advised to have a healthy diet and take folic acid to boost their immunity and manage the disease. Bone marrow transplant is the only cure for anemia though not done very often because of the weighty risk involved. Anemic patients should be active but intense and avoid strenuous exercise. They are also advised to avoid smoking for lung conditions, and alcohol that may cause dehydration.


Nacif, S. L., Mello. B. E., Pinheiro, S. R., Lima, R. F., Martino, R. B., Andraus, W., & D’Albuquerque, C. (2018). Successful liver transplantation case report from a deceased donor with sickle cell anemiaHindawi, 2018, 1-4.

Paula, T., Regena, S., Dana, S., Peyton, G., & Mary, H. (2019). CE: Understanding the complications of sickle cell disease. American Journal of Nursing, 119(6)26-36.

Vasundhara A. Krishna P. (2018). Computer aided technique to separate the red blood cells, categorize them and diagnose sickle cell anemia. Journal of Engineering Science and Technology Review12(12), 67-80.