Adult dose: The FDA limits total daily doses to 4000 mg; however the manufacturer of Tylenol suggests a limit of 3000mg per day pts with liver disease or chronic alcohol consumption are advised not to exceed 2000mg per day.
Class: Nonopioid analgesics
MOA: It blocks peripheral pain impulses by inhibition of prostaglandin synthesis Also lowers febrile body temperatures by acting on the hypothalamus, the structure in the brain that regulates body temperature.
Major side effects: blood disorders or dyscrasias (anemia’s), and nephrotoxicity’s, and hepatotoxicity’s (most serious), more common: skin disorders, N/V
Nursing considerations: allergy to acetaminophen, impaired hepatic function, chronic alcoholism, pregnancy, and lactation. Skin color, lesions.
Therapeutic monitoring: CBC, renal function and trough levels