Allergic Rhinitis: A Critical Discussion Analytical
Allergic rhinitis, which affects between 10-40% of the global population and up to 40% of children in the USA (Liu et al., 2010), is a common disabling inflammatory disease of the nasal airways characterized by typical nasal symptoms such as itching, sneezing, rhinorrhoea and airway constriction (Kim et al., 2010).Allergic Rhinitis: A Critical Discussion Analytical
Extant research has found nasal constriction to be the most dominant symptom resulting from allergic inflammation, and is indeed deemed as a critical symptom in patients presenting with allergic rhinitis (Hellings & Fokkens, 2006; Liu et al., 2010).
In the case scenario, the 4-year old patient has been diagnosed with IgE mediated allergic rhinitis, implying that the infection has an immunologic basis since IgE stands for immunoglobulin E (Burns, 2012; Hellings & Fokkens, 2006).Allergic Rhinitis: A Critical Discussion Analytical
Recent mechanistic studies have shown that the symptoms of allergic rhinitis “…result as a consequence of allergen-induced release and/or synthesis of a variety of pro-inflammatory mediators (including histamine, cytokines, arachidonic acid metabolites, chemokines, adhesion molecules, etc) from a variety of inflammatory cells (particularly mast cells, eosinophils and T-lymphocytes)” (Liu et al., 2010 p. 1150).